SPECT for beta therapy

Imaging with a CZT Compton camera

We leveraged our clinical SPECT design and demonstrated simultaneous imaging of Lu-177 and Tc-99m in a mouse phantom filled with both radionuclides.

Reference: Individual and Simultaneous Imaging of Tc-99m and Lu-177 With a Preclinical Broad Energy-Spectrum CZT-Based SPECT - P. M. C. C. Encarnaçao, P. M. M. Correia, B. Mehrdel, I. Bredwell, J. F. C. A. Veloso, J. Caravaca, Y. Seo, IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 9, no. 5, pp. 564-577, May 2025, doi: 10.1109/TRPMS.2025.3527874 (2025)

Clinical imaging of Lu-177

We designed a multi-head SPECT with an optimized collimator for imaging of the high-energy emission of Lu-177 (208 keV). We obtain a proof of principle in simulations of imaging of Lu-177 and Tc-99m.

Reference: Simulation studies of a full-ring, CZT SPECT system for whole-body imaging of Tc-99m and Lu-177, Y. Huh, J. Caravaca, J. Kim, Y. Cui, Q. Huang, G. Gullberg, Y. Seo. Med Phys. 2023; 50: 3726-3737

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