October 24th, 2025 – We presented our first in-vivo images of Ac-225 using a Compton camera at the WMIC 2025 conference. We demonstrated imaging of less than 1kBq of tumor uptake in a pilot study with three mice injected with only 18.5 kBq (0.5µCi). An image analysis reveals that the results correlate very well ex-vivo distributions.
More details in the recording of the presentation here.
June 6th, 2025 – We used a single-layer 3D positioning Compton camera (M400 from H3D, Michigan) and demonstrated imaging of Ac-225 daugthers (Bi-213 and Fr-221) in a mouse phantom filled with a low activity concentration.
October 18th, 2024 – We used a CZT detector without a collimator to dramatically increase gamma-ray detection efficiency and achieve nanocurie activity quantification in regions of interest defined by CT anatomical segmentation.
April 22nd, 2022 – We used Monte Carlo simulations to design and optimize a double-layer CZT Compton camera for small-animal imaging of extremely low activities of Ac-225.