Javier Caravaca
Imaging in Nuclear Medicine
Javier Caravaca
Imaging in Nuclear Medicine
Recent news
I presented our proof-of-principle for clinical imaging of Ac-225 therapy in a PET scanner. We employ the pioneering technique of time-of-flight cascade gamma-rays imaging (TOF-CGI) to enable direct imaging of Ac-225 in clinical PET scanners.
Oscar Matousek and myself were the guests of the third episode of a new LBL podcast. We talked about the origins of nuclear medicine at Lawrence Berkeley, the promising alpha therapy for cancer treatment, and the technologies we are developing to enable precision imaging for these therapies. Check it out below:
I was interviewed by Antonio G. Armas for the Spanish Live Radio show "Investigadores por el Mundo". You can listen to the interview below. Thanks to IMFAHE for making it possible.
In our new paper, we compare imaging performance of a single vs a double layer CZT camera, demonstrated a much better angular resolution for the double layer case in Ac-225 and Cs-137.
In case you missed it at the World Molecular Imaging Society (WMIS) 2025 conference, we just presented our first in-vivo images of Ac-225 with a Compton camera. We imaged as little as ~30nCi uptake in a prostate tumor model.
Check out our new paper on imaging of Actinium-225. Actinium-225 has demonstrated to be an excellent candidate for cancer treatment with alpha particles. However, in-vivo visualization of this radionuclide is difficult with current technology. In our new work, we demonstrated with in-vitro experiments that CZT Compton cameras provide a viable solution for this challenge.
In our new paper, we showed that dichroic filters can be used to enhance the Cherenkov/scintillation ratio in scintillator crystals (BGO and TlCl). This is a first step towards its application in TOF-PET to improve time-of-flight without compromising energy resolution.